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Updated 05 October 2026 · Source: CBSE board papers and marking schemes
Free · Class 12 Biology · 43 questions

Human Health & Disease: Class 12 Previous Year Questions

Every CBSE board exam question on Human Health & Disease (Class 12 Biology) from 2022 to 2026, with the years it was asked and the official marking-scheme answer in the free app.

Key facts

Human Health & Disease questions asked in CBSE board exams

Repeated questions first. Open the free app to see each question as it appeared in the paper, with its marking scheme.

  1. _________ Page 23 of 24 { } 33. (a) (i) Name the protozoan species that is responsible for causing the most serious and even fatal malarial disease. ½ (ii) Name the host in which the parasite completes its sexual stages and explain the changes taking place. 2 …
    Board 20265 markslong answer
  2. _________ Page 23 of 24 { } 33. (a) A 30 year old man was admitted to a hospital with recurrent infections, weight loss, prolonged fever. His blood report showed a decline in count of T-Lymphocytes thus affecting immune system. (i) Identify the disease and its…
    Board 20265 markslong answer
  3. There are limitations of traditional breeding techniques that led to promotion of micro-propagation ? (a) Mention two advantages of micropropagation. 2 (b) Give two examples where it is commercially adopted.
    Board 20263 marksshort answer
  4. _________ Page 17 of 24 { } 28. (a) A person inhales dust and pathogens but does not always fall sick. Explain how the body protects against such infections. 1 (b) Name and describe any two barriers involved in this protection. 2 _________ Page 18 of 24 { } …
    Board 20263 marksshort answer
  5. (a) Define Humoral immune response. 1 (b) Name any two types of antibodies found to give humoral immune response in humans.
    Board 20262 marksshort answer
  6. What is the role of histamine released by mast cells ? 1 (A) Lowers blood pressure (B) Causes allergic symptoms (C) Stimulates antibody formation (D) Destroys pathogens
    Board 20261 markMCQ
  7. The decrease in the T-Lymphocytes count in human blood will finally result in (B) (A) decrease in antigens decrease in antibodies (C) increase in antibodies (D) increase in antigens 9iPage (A)(A) (R) (R) (A) (B)(A) (R),(R) (A) 1 (C)(A) , (R)I (D)(A) , (R) 1 13…
    Board 20251 markAssertion-Reason
  8. Student to attempt either option-(A) or (B) : (A) Answer the following questions : (i) State what do you understand by ·MALT" ? Where it is located inside our body ? (i) Explain cytokine barriers. (i) Name the diagnostic test for AIDS. On what principle does i…
    Board 20255 markscase-based
  9. Student to attempt either option (A) or (B). (A) (i) Explain how is a bacterial cell made ·competent' to take up recombinant DNA from the medium. (ii) Explain the steps of amplification of gene of interest using PCR technique. OR (B) (i) What are transgenic an…
    Board 20255 markslong answer
  10. Immunity in our body is of two types : (i) Innate immunity and (i) acquired immunity. Innate immunity is a non-specific defence mechanism, whereas acquired immunity is pathogen-specific; it is called specific immunity too. Acquired immunity is characterised by…
    Board 20254 marksshort answer
  11. Samples of blood and urine of a sportsperson are collected before any sports event for drug tests. (a) Why there is a need to conduct such tests ? (b) Name the drugs the authorities usually look for. (c) Write the generic names of two plants from which these d…
    Board 20253 marksshort answer
  12. Student to attempt either option (A) or (B). (A) Describe any two situations where a medical doctor would recommend injection of a pre-formed antibodies (antitoxins)into the body of a patient. OR (B) The symptoms of malaria do not appear immediately after the …
    Board 20252 marksshort answer
  13. Assertion (A) : Streptococcus pneumoniae and Haemophilus influenzae are responsible for causing infectious disease in human beings. Reason (R) : A healthy person acquires the infection by inhaling the aerosols released by an infected person.
    Board 20251 markAssertion-Reason
  14. (a) Differentiate between humoral immune response and cell-mediated immune response. (b) Draw a schematic diagram of an antibody molecule and label any four parts.
    Board 20243 marksshort answer
  15. In a family, the father, the daughter and the son are colour blind, whereas the mother has normal vision. Do you think the son and the daughter have inherited the disease from their father ? Work out a cross to justify your answer.
    Board 20243 marksshort answer
  16. (a) A farmer while working on his farm was bitten by a poisonous snake. He was rushed to a nearby health centre where the doctor gave him an injection to save his life. (i) What did the doctor inject and why ? 1 2 1 (ii) Name the kind of immunity provided by t…
    Board 20242 marksshort answer
  17. In which of the following conditions/diseases is there a substantial increase in the activity of mast cells observed in the human body ? (A) Typhoid (B) Allergy (C) Ascariasis (D) AIDS
    Board 20241 markMCQ
  18. JJJJ Page 25 32. (a) A time-bound vaccination programme is followed for the children in our country from their birth up to ten years of age. A graph plotted below shows the effect of the vaccination followed by infection by the same pathogen, and the antibody …
    Board 20235 markslong answer
  19. JJJJ Page 27 30. The diagram shows the life cycle of a pathogenic protozoan. (i) 1 (ii) Write the changes the parasite undergoes in the liver. 1 (iii) Write the changes the parasite undergoes when it enters the RBC. 1 (iv) (a) 1 OR (iv) (b) At which stage duri…
    Board 20234 marksshort answer
  20. (a) Name the category of drugs represented by the chemical structure given above. (b) If the methyl group is substituted by acetyl group we get a bitter crystalline compound. Name the compound. (c) Name the natural source of these compounds. (d) State the harm…
    Board 20233 marksshort answer

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Frequently asked questions

How many marks does Human Health & Disease carry in the CBSE Class 12 Biology board exam?

Across recent CBSE board papers, Human Health & Disease carried about 8.2 marks per paper on average, making it number 3 of 13 chapters by weightage.

Which years were Human Health & Disease questions asked in CBSE boards?

Questions from Human Health & Disease appeared in the 2022, 2023, 2024, 2025, 2026 CBSE Class 12 board exams.

Where can I practise Human Health & Disease previous year questions for free?

On BoardPrep: all 43 Human Health & Disease questions are free to practise online, with official CBSE marking-scheme answers where published.