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Updated 05 October 2026 · Source: CBSE board papers and marking schemes
Free · Class 12 Chemistry · 39 questions

Biomolecules: Class 12 Previous Year Questions

Every CBSE board exam question on Biomolecules (Class 12 Chemistry) from 2022 to 2026, with the years it was asked and the official marking-scheme answer in the free app.

Key facts

Biomolecules questions asked in CBSE board exams

Repeated questions first. Open the free app to see each question as it appeared in the paper, with its marking scheme.

  1. Which of the following reactions is not explained by the open chain structure of glucose ? 1 (A) Glucose on prolonged heating with HI forms n-hexane. (B) Glucose reacts with hydroxylamine to form an oxime. (C) Glucose gets oxidized to gluconic acid on reaction…
    Board 20261 markAssertion-Reason
  2. Write the reactions of D-Glucose with the following : 3  1 (a) HI (b) Br2 water (c) Conc. HNO3
    Board 20263 marksshort answer
  3. Differentiate between the following : 2  1 (i) Peptide linkage and Glycosidic linkage (ii) Essential amino acids and Non-essential amino acids
    Board 20262 marksshort answer
  4. The base which is present in DNA but not in RNA is : 1 (A) Guanine (B) Cytosine (C) Thymine (D) Adenine
    Board 20261 markMCQ
  5. Proteins are polymers of -amino acids which are joined to each other by : 1 (A) Covalent Bond (B) Peptide Bond (C) Glycosidic Bond (D) Coordinate Bond { } 8 12.                 ? 1 …
    Board 20261 markMCQ
  6. (A) Define the following term : 2 + 1 (a) Reducing sugar (b) Differentiate between the following : (i) Fibrous proteins and globular proteins (ii) Nucleotide and nucleoside OR (B) Write the reaction of glucose with the following : 3  1 = 3 (a) H2N – OH (b) (C…
    Board 20263 marksshort answer
  7. The deficiency of which of the following vitamins causes increased fragility of red blood cells and muscular weakness : 1 (A) Vitamin A (B) Vitamin K (C) Vitamin E (D) Vitamin D { } 8   13  16  ,      –     (A)  …
    Board 20261 markMCQ
  8. Assertion (A) : Glucose gets oxidized to six carbon gluconic acid on reaction with bromine water. 1 Reason (R) : The carbonyl group is absent in the open chain structure of glucose.
    Board 20261 markAssertion-Reason
  9. Scurvy is caused due to deficiency of (A) Vitamin B1 (B) Vitamin B2 (C)Ascorbic acid (D) Glutamic acid (R) (A), (B), (C) (A) (A) (R) (R), (A) (B) (A) (R) , (R), (A) (C) (A) , (R) 1 (D) (A) , (R) 1 13. RUT (R) : 14. ()·C H,1 RUT (R) : C RUT (R) : 16. RUT (R).
    Board 20251 markAssertion-Reason
  10. Define the following terms : 28. 3×1=3 (a) Glycosidic linkage (b) Invert sugar (c) Oligosaccharides
    Board 20253 marksshort answer
  11. Write the reactions involved when D-glucose is treated with the following reagents : (1 + 1 = 2) (a) HCN (b) Br, water 11 22. =180go1-1) 100.20 1.86 K kg mol-1 3 0.512 K kg mol-1 I 23.(a·: (i) (b) f : E&2+/x = -2.36 V, E2/y = -0.14 V, 24.300 2050%350 [R = 8.31…
    Board 20252 marksshort answer
  12. (a) What is the difference between native protein and denatured protein ? (1 +1 +1= 3) (b) Which one of the following is a disaccharide ? Glucose, Lactose, Amylose, Fructose (c) Which vitamin is responsible for the coagulation of blood ? · 15 (a) (i) (1 + 1 = …
    Board 20253 marksshort answer
  13. Which of the following statements is not true about glucose ? (A) It is an aldohexose. (B) On heating with HI it forms n-hexane. (C) It exists in furanose form. (D) It does not give Schiff's test.
    Board 20251 markMCQ
  14. Assertion (A) : All naturally occurring ·-amino acids except glycine are optically active. Reason(R) : Most naturally occurring acids amino have L-configuration. 17. (A) : s (1 + 1 = 2) (a) (b) 18. fa f gf : (a) 2MnO7(aq) + 10I(aq) + 16H+(aq) ··) (b) Cr,02(aq)…
    Board 20251 markAssertion-Reason
  15. Which of the following is/are examples of denaturation of protein ? Coagulation of egg white (A) (B) Curdling of milk Clotting of blood (D) (C) Both (A) and (B)
    Board 20251 markMCQ
  16. {ZåZ{b{IV Ho$ {bE H$maU Xr{OE : 3 1=3 (H$) \ à{VñWmnZ A{^{H«$`mAm| _| Am°Wm}/n¡am {ZX}eH$ h¡ & (I) ao{g{_H$ {_lU Y«wdU AKyU©H$ hmoVm h¡ & (J) n- -AnK{Q>V hmo OmVm h¡ &
    Board 20243 marksshort answer
  17. Define the following terms : 2 1=2 (a) Denaturation of protein (b) Invert sugar
    Board 20242 marksshort answer
  18. Answer the following : (any three) 3 1=3 (a) What is peptide linkage ? (b) What type of bonds hold a DNA double helix together ? (c) Which one of the following is a polysaccharide ? Sucrose, Glucose, Starch, Fructose (d) Give one example each for water-soluble…
    Board 20243 marksshort answer
  19. Two among the three components of DNA are -D-2-deoxyribose and a heterocyclic base. The third component is : (A) Adenine (B) Phosphoric acid (C) Sulphuric acid (D) Uracil
    Board 20241 markMCQ
  20. Assertion (A) : Uracil base is present in DNA. Reason (R) : DNA undergoes self-replication.
    Board 20241 markAssertion-Reason

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Frequently asked questions

How many marks does Biomolecules carry in the CBSE Class 12 Chemistry board exam?

Across recent CBSE board papers, Biomolecules carried about 6.2 marks per paper on average, making it number 4 of 10 chapters by weightage.

Which years were Biomolecules questions asked in CBSE boards?

Questions from Biomolecules appeared in the 2022, 2023, 2024, 2025, 2026 CBSE Class 12 board exams.

Where can I practise Biomolecules previous year questions for free?

On BoardPrep: all 39 Biomolecules questions are free to practise online, with official CBSE marking-scheme answers where published.